Nutrient usually contains Di-Ammonium Phosphate, Di-Potassium Phospate, Tastone and Magnesium Sulfate while Energizer contains Diammonium phosphate, yeast hulls, magnesium sulphate, & Vitamin B Complex. Each has its special place in wine making. Nutrient is usually used by itself when making wine from grapes and is usually accompanied by energizer when making wine from anything else as most other fruit wines lack what is needed as far as nutrients and minerals to ferment properly. Grapes are the perfect fermentation vessel for making wine and can usually do a good job even without the help of nutrients but why take the chance.